The International and Cross-Straits Affairs Center, located under the Office of Research and Development, assumes the responsibility of promoting the establishment of an internationalized campus environment. It fosters cross-cultural communication and learning while providing assistance for various international exchange activities. In response to the growing trend of internationalization and in alignment with the educational goals of cultivating talented individuals with "humanistic technological literacy" and "applied practical intelligence," the center helps students expand their international perspectives. It assists them in develop international thinking and cross-cultural communication abilities, enhancing their competitiveness in the job market and improving their international mobility. As a result, the center aligns with the talent needs of multinational corporations.

Except the dissemination, promotion, and assist international students in necessary procedures to Taiwan, the recruitment of international students at Tainan University of Technology is not permitted to commission any external institution, legal person, group, or individual to handle related matters.